Product Includes
-
Application Dilution
Western Blot 1:500-1:2000
Immunofluorescence 1:200–1:400
Immunohistochemistry (Paraffin) 1:100–1:200
Immunofluorescence 1:200–1:400
Immunohistochemistry (Paraffin) 1:100–1:200
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 30% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
100mM Tris Glycine, 30% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Endogenous
Source / Immunogen
Synthetic peptide corresponding to residues surrounding Thr217 of human Tau protein
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]