Product Includes
Application Dilution
Immunofluorescence 1:400-1:800
Immunohistochemistry (Paraffin) 1:100-1:300
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Source / Immunogen
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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Reviews
IR102-426 anti-Survivin / BIRC5 antibody WB image
Survivin / BIRC5 antibody at 1/2000 dilution.
Lysates at 40 μg per lane. This blot was produced using a 15% SDS-PAGE. Nitrocellulose membrane was then blocked for an hour before being incubated with IR102-426 overnight at 4°C.
IR102-426 anti-Survivin / BIRC5 antibody _HepG2 ICC/IF image
Cells were fixed with 4% PFA for 10 min at RT, permeabilized with 0.1% NP-40 for 10 min at RT then blocked with 5% BSA for 30 min at RT. anti- Survivin / BIRC5 antibody (red) at 1:300 and 4°C. DAPI (blue) was used as the nuclear counter stain.
IR102-426 anti-Survivin / BIRC5 antibody_Colorectal carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Colorectal cancer tissue labeling Survivin / BIRC5 with IR102-426 at 1/150.
IR102-426 anti-Survivin / BIRC5 antibody_Tonsil carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Tonsil cancer tissue labeling Survivin / BIRC5 with IR102-426 at 1/150.