REACTIVITY | Hu、Ms、Rat |
---|---|
SENSITIVITY | Endogenous |
MW | 46-59 |
SOURCE | Rabbit-IgG |
Product Includes
Application Dilution
Immunohistochemistry (Frozen) 1:100 – 1:200
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Storage
This product is stable for 12 months when stored undiluted between 2°C and 8°C, protected from prolonged exposure to light. Do not freeze
Specificity / Sensitivity
Source / Immunogen
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]