Product Includes
Application Dilution
Immunofluorescence 1:200-1:500
Immunohistochemistry (Paraffin) 1:100-1:200
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Source / Immunogen
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
| Title | |
|---|---|
| 1 |
Application
Reactivity Human
|
| 2 |
Application
Reactivity Human
|
| 3 |
Application
Reactivity Human
|
Reviews
IR70-234 anti-MMP9 antibody WB image
MMP9 antibody - at 1/500 dilution. Lysates at 60 μg per lane. This blot was produced using a 7.5% SDS-PAGE. Nitrocellulose membrane was then blocked for an hour before being incubated with IR70-234 overnight at 4°C.
IR70-234 anti-MMP9 antibody WB image
MMP9 antibody - at 1/500 dilution
Lysates at 60 μg per lane. This blot was produced using a 7.5% SDS-PAGE. Nitrocellulose membrane was then blocked for an hour before being incubated with IR70-234 overnight at 4°C.
IR70-234 anti-MMP9 antibody_Colon carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Colon cancer tissue labeling MMP9 with IR70-234 at 1/100.
IR70-234 anti-MMP9 antibody_Breast carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human breast cancer tissue labeling MMP9 with IR70-234 at 1/100.
IR70-234 anti-MMP9 antibody_Kidney carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Kidney cancer tissue labeling MMP9 with IR70-234 at 1/100.
IR70-234 anti-MMP9 antibody_Kidney carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Kidney cancer tissue labeling MMP9 with IR70-234 at 1/100.
IR70-234 anti-MMP9 antibody ICC image
Immunofluorescence: cells were fixed with 4% paraformaldehyde for 10 min at RT, permeabilized with 0.1% NP-40 for 10 min at RT then blocked with 5% BSA for 30 min at room temperature. Cells were stained with IR70-234 anti- MMP9 antibody (red) at 1:250 and 4°C. DAPI (blue) was used as the nuclear counter stain.