Customer feedback IRR003 anti-RUNX2 antibody WB image

Catalog Number：IRR003

RUNX2, monoclonal antibody

Application

Reactivity Hu、Ms

REACTIVITY	Hu、Ms
SENSITIVITY	Endogenous
MW	55-65
SOURCE	Rat IgG2a

Product Includes

Application Dilution

Western Blot 1:1000-1:2000
Immunofluorescence 1:300-1:500

Storage

Phosphate-buffered solution, pH 7.2, containing 0.025% ProClin 300 , 20% Glycerol.
Store at -20°C.

Specificity / Sensitivity

Endogenous

Source / Immunogen

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]

#IRCP011

Hu、Ms、Rat

FNDC5 / irisin antibody