+1
Product Includes
-
Application Dilution
Western Blot 1:500-1:1000
Immunofluorescence 1:100-1:300
Immunohistochemistry (Paraffin) 1:50-1:150
Immunofluorescence 1:100-1:300
Immunohistochemistry (Paraffin) 1:50-1:150
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Specificity / Sensitivity
Endogenous
Source / Immunogen
-
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]