Product Includes
Application Dilution
Immunofluorescence 1:200–1:300
Immunohistochemistry 1:100
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Source / Immunogen
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| Title | |
|---|---|
| No data. | |
Reviews
IR257-914 anti-CD11b / ITGAM antibody WB image
Anti-CD11b / ITGAM antibody - at 1/500 dilution
Lysates/proteins at 50 μg per lane.
This blot was produced using a 5% SDS-PAGE. Nitrocellulose membrane was then blocked for an hour before being incubated with IR257-914 overnight at 4°C.
Customer feedback Image IR257-914 anti-CD11b / ITGAM antibody IHC image
Immunohistochemical analysis of paraffin embedded mouse tissue labeling CD11b / ITGAM with IR257-914 at 1/100.
Sample: Mouse CT26 tumor
Antigen retrieval: Citrate buffer pH6