Catalog Number：IR250-898

CD4 antibody

Application

Reactivity Hu

REACTIVITY	Hu
SENSITIVITY	Endogenous
MW	55-72
SOURCE	Rabbit-IgG

Product Includes

Application Dilution

Western Blot 1:500 – 1:1000
Immunohistochemistry (Paraffin) 1:200 – 1:400
Flow Cytometry 1:100

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative

Specificity / Sensitivity

Endogenous

Source / Immunogen

Synthetic peptide / Extracellular domain corresponding to Human CD4

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

#IR251-890

CD8 antibody