Product Includes
Application Dilution
Immunofluorescence 1:100–1:200
Immunohistochemistry (Paraffin) 1:100
Storage
100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
Specificity / Sensitivity
Source / Immunogen
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
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Reviews
IR219-807 anti c-MET antibody WB image
All lanes : Anti c-MET antibody at 1/700 dilution
Lysates/proteins at 50 μg per lane
This blot was produced using a 5% SDS-PAGE. The gel was run at 140V for 50 minutes before being transferred onto a Nitrocellulose membrane at 18V for 60 minutes. The membrane was then blocked for an hour before being incubated with IR219-807 overnight at 4°C.
IR219-807 anti c-MET antibody WB image
All lanes : Anti c-MET antibody at 1/700 dilution
Lysates/proteins at 50 μg per lane
This blot was produced using a 5% SDS-PAGE. The gel was run at 140V for 50 minutes before being transferred onto a Nitrocellulose membrane at 18V for 60 minutes. The membrane was then blocked for an hour before being incubated with IR219-807 overnight at 4°C.
IR219-807 anti c-MET antibody WB image
All lanes : Anti c-MET antibody at 1/1000 dilution
Lysates/proteins at 50 μg per lane
This blot was produced using a 10% SDS-PAGE. The gel was run at 140V for 50 minutes before being transferred onto a Nitrocellulose membrane at 18V for 60 minutes. The membrane was then blocked for an hour before being incubated with IR219-807 overnight at 4°C.
IR219-807 anti c-MET antibody WB image
All lanes : Anti c-MET antibody at 1/800 dilution
Lysates/proteins at 50 μg per lane
This blot was produced using a 5% SDS-PAGE. The gel was run at 140V for 50 minutes before being transferred onto a Nitrocellulose membrane at 18V for 60 minutes. The membrane was then blocked for an hour before being incubated with IR219-807 overnight at 4°C.
IR219-807 anti c-MET antibody WB image
All lanes : Anti c-MET antibody at 1/800 dilution
Lysates/proteins at 50 μg per lane
This blot was produced using a 5% SDS-PAGE. The gel was run at 140V for 50 minutes before being transferred onto a Nitrocellulose membrane at 18V for 60 minutes. The membrane was then blocked for an hour before being incubated with IR219-807 overnight at 4°C.
IR219-807 anti c-MET antibody_Breast carcinoma IHC image
Immunohistochemical analysis of paraffin embedded Human Breast cancer tissue labeling c-MET with IR219-807 at 1/100.
IR219-807 anti c-MET antibody IHC image
Immunohistochemical analysis of paraffin embedded Human cancer tissue labeling c-MET with IR219-807 at 1/100