Exosome
CD31
Antibodies Panel
Latest News
2022-11-10 11:00

Cell Junction Antibodies

Cell junctions regulate small-molecule trafficking between cells, the organization of cells into tissues, and the adherence of cells to each other and the extracellular matrix. Dysfunctional junctions are implicated in several diseases, including cancer, neurodegeneration, and cardiovascular dysfunction. Understanding cell junctions is fundamental to understanding disease pathology.

There are many types of cell junctions:

  • Gap junctions—tightly packed channels that allow small molecules to travel between cells.
  • Tight junctions—barriers that regulate the paracellular movement of solutes down their electro-osmotic gradients.
  • Adherens junctions—main components include cadherins and catenins that form cell-cell junctions signaling

Highlighted Products

Cell Junction Antibodies
Catalog Component Clonality Reactivity App
IR64-190 Claudin-1 / CLDN1 antibody Rab-pAb H, M, R WB, IF, IHC
IR57-195 OCLN / Occludin antibody Rab-pAb H, M, R WB, IF, IHC
IR56-184 ZO-1 antibody Rab-pAb H, M, R WB, IF, IHC
IR55-180 E-cadherin antibody Rab-pAb H, M, R WB, IF, IHC
IR49-149 Beta-catenin Rab-pAb H, M, R WB, IF, IHC

Applications of Cell Junction Antibodies:


References:

  • Cell Junctions, Molecular Biology of the Cell. 4th edition.