Immunohistochemical Study of Nrf2-Antioxidant Response Element as Indicator of Oxidative Stress. The Nrf2 transcription factor is a master regulator of the cellular defense against oxidative and electrophilic stress. An increase in Nrf2 protein levels and an accumulation of Nrf2 in the nucleus are key parts of the Nrf2 activation mechanism.
NRF2 has turned out to be a key activator of cancer-supportive anabolic metabolism. diverse roles played by NRF2 in cancer focusing on metabolic reprogramming and tumor-promoting inflammation.
Highlighted Products
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Metabolism Cardiovascular Antibodies |
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Catalog |
Product Name |
Clonality |
Reactivity |
App |
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FNDC5 antibody |
Rab-pAb |
H, M, R |
WB, IHC |
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E-selectin antibody |
Rab-pAb |
H, M, R |
WB, IHC |
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P-selectin antibody |
Rab-pAb |
H, M, R |
WB, IHC |
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Troponin T antibody |
Rab-pAb |
H, M, R |
WB, IHC |
|
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Troponin I antibody |
Rab-pAb |
H, M, R |
WB, IHC |
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Desmin monoclonal antibody |
Mus-mAb |
H, M, R |
WB, IF, IHC |
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CD142 antibody |
Rab-pAb |
H, M, R |
WB, IHC |
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RUNX2 monoclonal antibody |
Rab-pAb |
H, M, R |
WB |
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NRF2 antibody |
Rab-pAb |
H, M, R |
WB, IF, IHC |
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References :
1. Toxicol Lett. 2015 October 14; 238(2): 83–89.
2. Carcinogenesis. 2020 Jun; 41(4): 405–416.